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State Cannabis Legalization and Cannabis Use Disorder in the US Veterans Health Administration, 2005 to 2019

In this observational study of sequential yearly Veterans Health Administration electronic health record data from 2005 to 2019, CUD rates increased from 1.38% to 2.25% in states with no cannabis legalization, 1.38% to 2.54% in states that legalized medical use, and 1.39% to 2.56% in states that legalized recreational use. Significant but small effect sizes were found for medical and recreational legalization, accounting for 4.7% and 9.8% of the overall increases in the respective states.

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